Jorge E. Galán
The information listed below is current as of the date the transcript was finalized.
Abstract of Interview
Jorge E. Galán was born in Pellegrini, a small town near Buenos Aires in Argentina. His father was a businessman, dealing with agriculture, his mother a homemaker. He had one older sister and one younger. While he still lived at home, he attended political and business meetings with his father and became very interested in politics. When Galán was 12, he was sent to a Salecian boarding school in Santa Rosa. After high school he decided to attend the University of La Plata, where he received his Doctor of Veterinary Medicine and his Doctor of Veterinary Science. He became interested in infectious diseases, particularly in horses, and was accepted to the PhD program at the veterinary school at Cornell University. There he discovered his major interest, the clever Salmonella bug. He worked for several years in Roy Curtiss' lab at Washington University in St. Louis before he started his own lab at SUNY Stony Brook. There he discovered Type III protein secretion system; and he continued to study Salmonella. He continues to work most hours of every day in his lab, to teach, and to mentor his graduate students and postdoctoral students.
|1980||University of La Plata||DVM|
|1982||University of La Plata||Dr of Vet Sc|
Washington University in St. Louis
State University of New York at Stony Brook
|1982 to 1984||
Organization of American States Fellowship
|1984 to 1986||
New York State Fellowship
James M. Sherman Award to Outstanding Graduate Research in
|1990 to 1994||
Pew Scholar in the Biomedical Sciences
Searle-Chicago Community Trust Scholar
Sinsheimer Scholar in the Biomedical Sciences
Established Investigator, American Heart Association
Table of Contents
Catholic boarding school in Argentina. Family background. Early interest in politics. Veterinary training at the University of La Plata, Argentina. Research on infectious diseases prompts Galán to pursue further study abroad.
Enters Cornell University as a doctoral student in veterinary school. Performs research on neonatal immunological response to Streptococcus equi in the John F. Timoney lab. Introduces new techniques to veterinary medicine. Medical field’s lack of response to veterinary pathogen research. Postdoc at Roy Curtiss III lab at Washington University. Investigates Salmonella pathogenesisin the Curtis's lab.
Galán starts own lab at State University of New York at Stony Brook. Discovery of Type III protein secretion system. Uses scanning electron microscopy to observe Salmonella-cell interaction. Salmonella-induced cytoskeletal rearrangement. Epidermal growth factor (EGF) receptor activated by Salmonella--Cross-talk cellular responses to Salmonella invasion. Tyrosine phosphatase enzyme potentially a signaling molecule. Evolution's effect on Salmonella and host.
Science funding. Selecting postdocs and graduate students for lab. Strong motivation a prerequisite in lab. Galán's commitment to science leaves little time for other activities. His lab's writing skills. Field's initial response to work on Salmonella-cell interaction. Proposed work on how bacteria enter a nonphagocytic cell. How to prepare for a research career in microbial pathogenesis. Pharmacological applications for Galán's research on protein secretion mechanisms. Practical applications of Salmonella research.